At the beginning of this century, debates regarding what are the main control mechanisms that ignite the action potential (AP) in heart pacemaker cells dominated the electrophysiology field.The original theory which prevailed for over 50 years had advocated that the ensemble of surface membrane NAIL/DOMES ion channels (i.e., M clock) is sufficient
EFISIENSI TEKNIS BADAN USAHA MILIK DAERAH (BUMD) BIDANG JASA PRODUKSI PROVINSI JAWA TENGAH
This research was aimed to analyze the level of technical efficiency and identify some factors that influence it and also solutions necessary to conduct to improve the efficiency of BUMD of production service field in Central Java Province.The analysis method used a Data Envelopment Analysis (DEA) by a frontier analysis approach.The BUMN analysis u
Modeling Water Motion near Seismic Waves Propagating across a Graded Seabed, as Generated by Man-Made Impacts
Seismic interface waves generated by seabed impacts are believed to have biological importance.Various wave types are of interest to seismologists, who can minimize the unwanted, but often dominant, ground roll waves with suitable instrumentation.Waves made by dredging and piling have been measured using geophones and found to be of this interface
Iron in intracellular infection: to provide or to deprive?
Due to their chemical versatility, transition metals were incorporated as cofactors for several basic metabolic pathways in living organisms.This same characteristic makes them potentially harmful, since they can be engaged in deleterious reactions like Fenton chemistry.As such, organisms have evolved highly specialized mechanisms to supply their o